Author : Ashwin singh chouhan
Keyword : Streptozotocin, brassica oleracea, momordica charantia, column chromatography, hptlc
Subject : Medical research
Article Type : Original article (research)
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Abstract : Abstract: Diabetes mellitus is one of the common metabolic disorders with micro-and macrovascular complications that results in significant morbidity and mortality. It is considered as one of the five leading causes of death in the world. In modern medicine no satisfactory effective therapy is still available to cure diabetes mellitus there is increasing demand by patients to use natural products with anti diabetic activity due to side effects associated with the use of insulin and oral hypoglycemic agents. Medicinal plants continue to provide valuable therapeutic agents, both in modern and in traditional medicine. Brassica oleracea and Momordica charantia juice has hypoglycaemic effects on blood glucose concentrations of diabetic rats and may be effective in cases of glucose tolerance impairment. However, it can be speculated that the antidiabetic activity of C Brassica oleracea and Momordica charantia juice may be due to non-specific mechanism and not due to the stimulation of insulin release from pancreatic beta cells since streptozotocin used in this study is well known to work by depleting the pancreatic beta cells thus reducing the release of insulin from these cells. Also, the synergistic effect of different bioactive chemicals may have a crucial contribution to the potential hypoglycaemic action of the plant species.
Article by : ASHWIN SINGH CHOUHAN
Article add date : 2022-01-23
How to cite : Ashwin singh chouhan. (2022-January-23). Anti-diabetic activity of brassica oleracea var italica and momordica charantia linn on streptozotocine induced diabetes. retrieved from https://www.openacessjournal.com/abstract/980