Author : Naina mohamed pakkir maideen
Keyword : Drug interactions, potassium-sparing diuretics, spiranolactone, eplerenone, amiloride, triamterene
Subject : Pharmacology
Article Type : Review article
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Abstract : Potassium-sparing diuretics are useful in the treatment of resistant hypertension and salt sensitive forms of hypertension common in black, obese, diabetic and elderly patients and they include Spironolactone, Eplerenone, Amiloride and Triamterene. Potassium-sparing diuretics interact pharmacodynamically with the drugs such as ACE inhibitors, angiotensin receptor blockers, direct renin inhibitor, potassium supplements, trimethoprim and cyclosporine and elevate the risk of hyperkalemia. To predict and prevent the adverse drug interactions, the prescribers and the pharmacists are needed to be aware of the possible drug interactions of Potassium-sparing diuretics.
Article by : Naina Mohamed Pakkir Maideen
Article add date : 2021-12-21
How to cite : Naina mohamed pakkir maideen. (2021-December-21). Pharmacologically relevant drug interactions of potassium-sparing diuretics. retrieved from https://www.openacessjournal.com/abstract/949