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Naina Mohamed Pakkir Maideen

(Dubai Health Authority)

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Drug interactions
α-glucosidase inhibitors
acarbose
miglitol
voglibose

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Pharmacologically relevant drug interactions of α-glucosidase inhibitors

Author : Naina mohamed pakkir maideen

Keyword : Drug interactions, α-glucosidase inhibitors, acarbose, miglitol, voglibose

Subject : Diabetes

Article Type : Review article

DOI : 10.15406/jdmdc.2019.06.00178

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Abstract : The α-glucosidase inhibitors are antidiabetic agents suppressing the postprandial hyperglycemia and they include Acarbose, Miglitol and Voglibose. These drugs could be used alone or as add-on therapy to treat patients with type 2 diabetes taking other antidiabetic drugs. The gastrointestinal motility is increased by the administration of Acarbose, which may lead to decreased absorption of Digoxin and Metronidazole. The glucose lowering effects of antidiabetic drugs such as Metformin, Glibenclamide, Rosiglitazone, Vildagliptin and Dapagliflozin might be enhanced by the coadministration of α-glucosidase inhibitors, though there were reports of little or no alterations in the pharmacokinetics properties of them.

Article by : Naina Mohamed Pakkir Maideen

Article add date : 2021-12-21


How to cite : Naina mohamed pakkir maideen. (2021-December-21). Pharmacologically relevant drug interactions of α-glucosidase inhibitors. retrieved from https://www.openacessjournal.com/abstract/939

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