Increase your published paper (Manuscript) citation

Naina Mohamed Pakkir Maideen

(Dubai Health Authority)

Author Details

1. Naina mohamed pakkir maideen

Author Statistics

Views : 327

Downloads : 126


Article Statistics

0
This article cited by 0

Search By Keyword

 metformin  drug interactions  organic cation transporters  multidrug and toxin extruders  pharmacokinetic interactions

Article File

PDF

Drug interactions of metformin involving drug transporter proteins

Author : Naina mohamed pakkir maideen

Keyword :  metformin  drug interactions  organic cation transporters  multidrug and toxin extruders  pharmacokinetic interactions

Subject : Diabetes

Article Type : Review article

DOI : 10.15171/apb.2017.062

Article QR Code

Drug interactions of metformin involving drug transporter proteins QR Code

Article File : Full Text PDF

Abstract : Metformin is a most widely used medication all around the world to treat Type 2 diabetes mellitus. It is also found to be effective against various conditions including, Prediabetes, Gestational diabetes mellitus (GDM), Polycystic Ovarian Syndrome (PCOS), Obesity, Cancer, etc. It is a cationic drug and it depends Organic Cation Transporters (OCTs) and Multidrug and Toxin Extruders (MATEs) mostly for its pharmacokinetics movement. The probability of drug interaction increases with the number of concomitant medications. This article focuses the drug interactions of metformin and most of them are linked to the inhibition of OCTs and MATEs leading to increased plasma metformin concentrations and subsequent elevation of risk of Metformin Associated Lactic Acidosis (MALA). By identifying the drugs inhibiting OCTs and MATEs, the healthcare professionals can predict the drug interactions of metformin.

Article by : Naina Mohamed Pakkir Maideen

Article add date : 2021-12-21


How to cite : Naina mohamed pakkir maideen. (2021-December-21). Drug interactions of metformin involving drug transporter proteins. retrieved from https://www.openacessjournal.com/abstract/929

Power structure and socio-political milieu in ellis’s the forgotten cottage: a new historical study

Laiba khan and rana abdul munim khan
Date : 2020-06-06
10.55737/qjss.310479359
This article analyses and evaluates the novel The Forgotten Cottage by Courtney Ellis, which focuses on the exploration of historical and socio-politi...

Empirical research on the mediating impact of integration between supply chain management practices and supply chain management performance

Amna ali, fazli haq, athar marwat, shiraz khan and adil adnan
Date : 2020-06-06
10.55737/qjss.799071365
A growing institutional framework concerning Pakistan's pharmaceutical industry supply chain integration and supply chain management practices is sign...

Prevalence of intimate partner violence in the muslim community of pakistan and the fundamental religious perspective of islām (sharī‘ah)

Sadia mushtaq, hafsah ayaz qureshi, almees jabbar and naila mushtaq
Date : 2020-06-06
10.55737/qjss.317943363
This paper explores the prevalence of Intimate Partner Violence, especially emotional abuse, in Pakistan and discusses the fundamental religious persp...

Evaluation of critical thinking elements: a qualitative content analysis of physics textbook grade ix

Muhammad jamil, tahira batool bokhari and dawood ahmad
Date : 2020-06-06
10.55737/qjss.337110358
Critical thinking skills are essential in the 21st century in all academic and overall life. This skill is among the 4Cs of the twenty-first century t...

Scrutinizing public-private sector investment spending and budgetary deficit in the health sector of pakistan: a time series approach

Khawaja asif mehmood, fareeha riaz, farzana munir, sidra ilyas and muhammad aurmaghan
Date : 2020-06-06
10.55737/qjss.673117356
The public and private sector spending is crucial for appropriate resource allocation. Private sector spending makes the government to be lenient sinc...

Emotional intelligence and emotional self-regulation: a qualitative case study of undergraduate university students in peshawar

Tabassum faiz solehria and syed munir ahmad
Date : 2020-06-06
10.55737/qjss.993100318
This study sought to explore the interplay between emotional intelligence and emotional self-regulation in undergraduate university students. This stu...

Artificial intelligence and machine learning in legal research: a comprehensive analysis

Muhammad hamza zakir, sobia bashir, rafia naz ali and syed hammad khan
Date : 2020-06-06
10.55737/qjss.203679344
This paper conducts a thorough investigation into the profound ramifications of Artificial Intelligence (AI) and Machine Learning (ML) on legal procee...

Public interest litigation in pakistan: unveiling its features, roles, and potential for ensuring justice for all

Mubashar tariq, hafiz muhammad azeem and muhammad zahid rafique
Date : 2020-06-06
10.55737/qjss.738424337
The regular court system is failing to provide justice for all in Pakistan's legal landscape. However, a powerful tool exists to ensure justice for al...