Author : Wudneh ketema moges
Keyword : Schizophrenia; relapse; recurrent events; ph models, frailty models
Subject : Health
Article Type : Original article (research)
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Abstract : Schizophrenia is a chronic psychiatric disorder with a modest treatment outcome. In addition, relapses are usual. The time among relapses are rarely considered in studies. The aim of this study was to investigate the associated factors that affect time to relapses in schizophrenic patients at ST. Amanuel mental specialized hospital with recurrent events model in survival analysis. Medical records of 332 individuals with schizophrenia were examined covering a two year period. The distributions of number of relapses were 162.The parametric frailty models were used to determine the correlation between discharge times and relapse and to identify risk factors. The unobserved heterogeneity in individual and correlation between relapses as estimated by the Weibull-gamma frailty model was (p-value=0.000) and Kendall's Tau (Γ) =0.498. This indicated that there was heterogeneity among the participants and correlation between relapses. The final model showed that the effect of comorbidity (HR= 6.522, p-value=0.000), employment status (HR= 5.334, p-value =0.001), history of suicide attempt (HR= 2.167, p-value=0.003) and history of traditional treatment (HR= 1.973262, p-value=0.021) were significant on the hazard time to relapses.
Article by : Wudneh Ketema Moges
Article add date : 2021-08-31
How to cite : Wudneh ketema moges. (2021-August-31). Predictors of time to relapses among schizophrenic patients in st.amanuel mental specialized hospital, addis ababa, ethiopia. retrieved from https://www.openacessjournal.com/abstract/833