Author : Sultan ahmad; aqeel ahmad; alkama aziz
Keyword : Malaria; plasmodium falciparum; drug resistance; artemisinin; k13
Subject : Biotechnology
Article Type : Review article
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Abstract : Malaria is caused by Plasmodium species of which P. falciparum is the most lethal. All the clinical symptoms of malaria are attributed to the blood stage of the parasite’s life cycle. The propagation of the blood-stage requires repeated cycles of erythrocyte invasion and multiplication. All pathogenesis and death associated with Plasmodium falciparum malaria are due to parasite-infected erythrocytes. Invasion of erythrocytes by P. falciparum merozoites requires specific interactions between host receptors and parasite ligands that are localized in apical organelles called micronemes. The blood stage of malaria parasites is responsible for all the morbidity and mortality associated with malaria. During the blood stage, malaria parasites invade and multiply within host erythrocytes. The process of erythrocyte invasion requires specific interactions between host receptors and parasite ligands.
Article by : Sultan Ahmad
Article add date : 2020-08-16
How to cite : Sultan ahmad, aqeel ahmad, alkama aziz. (2020-August-16). An update on malaria vaccine candidates rtsas01, artimisnine and k13. retrieved from https://www.openacessjournal.com/abstract/77