Author : Sofia khanam, firdous sm
Keyword : Morin, bioflavonoids, antioxidant, oxidative stress, free radical.
Subject : Pharmacology
Article Type : Review article
DOI : 10.5958/0974-360x.2020.00797.0
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Abstract : Phytochemicals including bioflavonoids are active metabolites extensively present in plants. It is potent antioxidants provide that beneficial effects against oxidative stress-related diseases. The present literature survey was carried out to explore the reported antioxidant activity of morin. Morin exerts different biological activities viz., antidiabetic, anti-inflammatory, antihypertensive, antitumoral, antibacterial, and neuroprotective effects by regulating the activity of different antioxidant enzymes. In addition, morin exerts various biological activities such as xanthine oxidase inhibition, protective effect of DNA from damage caused by free radical, free radical scavenging activity, cell proliferation inhibitor property, hepatoprotective, hypolipidemic, antidiabetic, and neuroprotective activity. From the literature review it was found that most of these activities of morin are due to increase in the endogenous antioxidant activities viz., superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx). Based on our findings, we enlighten the prospective role of morin hydrate as an antioxidant.
Article by : Sofia Khanam
Article add date : 2021-06-11
How to cite : Sofia khanam, firdous sm. (2021-June-11). Morin combat against oxidative stress induced different diseases in experimental models: a review. retrieved from https://www.openacessjournal.com/abstract/760