Author : Ramu samineni, jithendra chimakurthy
Keyword : Co-crystal, intrinsic solubility, in vitro dissolution, maximum electroshock seizure.
Subject : Pharmacy
Article Type : Original article (research)
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Abstract : Drug readily crosses the blood-brain barrier and enters the central nervous system [2] Pharmacokinetic data Pharmaceutical co-crystals Pharmaceutical co crystals are unit crystalline elements made up of an API and one or more coformer or other API, at room temperature co crystals are solid. Benzoic Acid were purchased from the Sigma-Aldrich chemical Pvt. Ltd, Salicylic were purchased from the Merck specialities Pvt. Ltd and Tartaric Acid were purchased from the Thermo Fisher Scientific India Pvt. Ltd. In current research double distilled water, solvents used for analytical grade Methods: Preparation of co-crystal by solvent evaporation: Solution was cooled to room temperature and kept for slow evaporation for 6 h. the crystals were isolated by filtration through a membrane (0.45 pm) and dried in the air (102) flow process shown in figure 3, 4 Preparation of co-crystal by solvent drop method: Fourier Transform …
Article by : RAMU SAMINENI
Article add date : 2020-11-03
How to cite : Ramu samineni, jithendra chimakurthy. (2020-November-03). Effect of coformers on novel co-crystals of gabapentin: an in vivo approach. retrieved from https://www.openacessjournal.com/abstract/347