Author : Suman kumari
Keyword : Thrombocytopenia, platelets,megakaryocytes
Subject : Pathology
Article Type : Original article (research)
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Abstract : AIMS/OBJECTIVES: To study cases of thrombocytopenia on the basis of bone marrow findings and correlate it with clinical findings and hematological parameters. To study the role of morphological examination of bone marrow aspirate in the diagnosis of various disorders leading to thrombocytopenia and classify them. METHODS: It was a retrospective study on 100 patients who presented with persistent thrombocytopenia either isolated or combined with other cytopenias in tertiary care hospital in 2022. Complete clinical details were recorded. Routine hematological investigations like CBC were performed using an automated cell counter. A detailed peripheral blood examination was done. A bone marrow examination was done in every case and findings were recorded. The final diagnosis was listed under 2 categories: neoplastic and non-neoplastic. RESULT: A total of 100 cases were included in our study and categorized into neoplastic and non-neoplastic. The most common neoplastic condition was acute leukemia, and the most common non-neoplastic condition was megaloblastic anemia followed by ITP. The overall most common condition was megaloblastic anemia. The age distribution of patients varied over a wide range from 9 months to 83 years of age. The most common clinical feature was generalized weakness followed by progressive pallor, fever, bleeding tendencies, etc. CONCLUSION We concluded that thrombocytopenia is not a disease, but it is an entity that can be seen in a number of clinical problems including neoplastic and non-neoplastic diseases. We also found that bleeding is not a very common manifestation in thrombocytopenia and moreover few patients with very low platelet counts had no bleeding manifestation.
Article by : SUMAN KUMARI
Article add date : 2023-03-01
How to cite : Suman kumari. (2023-March-01). Clinico hematological pattern of patients presenting with thrombocytopenia. retrieved from https://www.openacessjournal.com/abstract/1206