Author : Mohammed shahab uddin
Keyword : Covid-19, severe acute respiratory syndrome coronavirus 2, pediatric multisystem inflammatory disease, covid-19 related, coronary aneurysm, case reports, covid-19 diagnostic testing
Subject : Medical
Article Type : Case report
DOI : 10.12659/ajcr.933053
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Abstract : Background: Early in the COVID-19 pandemic, children who were infected with severe acute respiratory syndrome coronavirus2 (SARS-CoV-2) with vascular inflammation were described as having a vasculitis similar to Kawasaki’s disease. There are now consensus clinical guidelines that have described the presentation and diagnosis of multisystem inflammatory syndrome in children (MIS-C) associated with SARS-CoV-2 infection. This report aims to describe a case of MIS-C in an 11-year-old Saudi Arabian girl who presented with coronary artery aneurysm and cardiac involvement. Case Report: We describe an 11-year-old Saudi girl who was asymptomatic for 3 weeks after contracting SARS-CoV-2. Three weeks after suffering a mild flulike illness, she developed a high fever, cough, and severe clinical deterioration within 12 h of admission, including shock, rash, pleural effusion, high inflammatory markers, and a coronary aneurysm. As per current practice, the diagnosis was confirmed as multisystem inflammatory syndrome based on a SARS-CoV-2 test with reverse transcription polymerase chain reaction (RT-PCR) from 2 nasopharyngeal aspirates. Her condition was successfully treated with antibiotics, inotropes, IVIG, aspirin, and Tocilizumab, in addition to high-flow oxygen therapy. Eventually, she was able to return home after fully recovering. Conclusions: The findings in this report suggest that children with MIS-C due to SARS-CoV-2 infection can have a good prognosis, even when they suffer from coronary artery and cardiac involvement. The increasing number of emerging SARS-CoV-2 variants that affect children supports the importance of RT-PCR for the COVID-19 diagnostic test for children with multisystem or cardiovascular inflammation, which may guide the most appropriate clinical management of the variants of MIS-C.
Article by : Mohammed Shahab uddin
Article add date : 2023-02-13
How to cite : Mohammed shahab uddin. (2023-February-13). An 11-year-old saudi arabian girl who presented with multisystem inflammatory syndrome in children (mis-c) associated with sars-cov-2 infection with coronary artery aneurysm and cardiac involvement: a case report. retrieved from https://www.openacessjournal.com/abstract/1183