Author : Milton l pozo md facp
Keyword : Prevention, treatment of sars-cov-2, clinical review
Subject : Medicine
Article Type : Review article
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Abstract : We have learnt that although most human coronaviruses cause mild upper respiratory tract disease, they may be associated with severe multisystemic disease in all ages, particularly in immune-compromised individuals. The clinical experience with SARS-CoV-2 shows that CoV2 can present with multiple disease patterns ranging from mild upper respiratory tract illness to Severe Acute Respiratory Syndrome and Acute Respiratory Distress Syndrome in nearly 10% mortality; as a Systemic Coagulopathy, as a Cytokine Storm and as a Multisystem Organ Failure. In the absence of an effective medication or vaccine only those who have a strong natural resistance are expected to navigate the current pandemia. Further, a diminished immune system integrity and response caused by age, chronic metabolic, immunological, environmental and infectious illnesses greatly increase the risk of a severe disease and dismal outcome. Developing therapeutic regimes for SARSâ€CoV-2 requires proper understanding of the disease(s) it causes. The pathogenesis of the virus, its genomics and structural biology and the host immune response pattern after infection. In addition to the knowledge on the structural makeup, a critical understanding of the life cycle and pathogenesis of SARSâ€CoV-2, is essential. Finally, the biochemistry and molecular pharmacology of the proposed drug. The current challenge is conducting clinical trials on an urgent basis and determining the effectiveness and safety of different drugs alone or in combination. The objectives of this clinical review are: 1.- Present to the medical community and the public a large another approach that should reverse the current perceived nihilism. The proposed solution invokes: a) the prevention of the latching of SARS-CoV-2 to the nasal epithelium and b) incrementing the immunity of the population at large, especially those most disadvantaged from the immunological point of view by the administration of Inosine Pranobex, that has along tract recor
Article by : MILTON L POZO MD
Article add date : 2020-09-03
How to cite : Milton l pozo md facp. (2020-September-03). Prevention and treatment of sars-cov-2, a clinical review. retrieved from https://www.openacessjournal.com/abstract/110